Why Does Ozempic Cause Sulfur Burps? (And What Actually Helps)

If you've started a GLP-1 medication like Ozempic, Wegovy, Mounjaro or Zepbound and suddenly noticed burps that smell like rotten eggs, you're not imagining it — and you're far from alone. These "sulfur burps" are one of the most-reported and most-unpleasant digestive side effects of GLP-1 therapy. The good news: there's a clear reason they happen, and several practical ways to reduce them.

What causes sulfur burps on a GLP-1?

GLP-1 medications work in part by slowing down how quickly your stomach empties (a process called delayed gastric emptying). That's part of why they help you feel full for longer.^[1] But there's a trade-off: when food lingers in the stomach and upper gut, it has more time to ferment. That fermentation produces hydrogen sulfide — a gas with an unmistakable rotten-egg smell — which can come back up as a burp.^[2][3]

Belching is documented in GLP-1 clinical trials: in Wegovy studies, eructation (belching) was reported in roughly 5.8% of patients versus 0% on placebo.^[4] Higher-fat and larger meals, and higher doses, tend to make it worse.

How long do sulfur burps last?

For many people, the worst of it eases within a few weeks as the body adjusts, or after a dose is stabilized. That said, it can flare after specific meals. If your sulfur burps are severe, persistent, or come with vomiting or severe pain, talk to your prescriber — don't just push through it.

What actually helps

1. Adjust how and what you eat

• Smaller, lower-fat meals. Big, greasy meals sit longest and ferment most.
• Eat slowly and don't overfill. Since your stomach empties slower, it fills faster.
• Stay hydrated. Water supports digestion and helps things keep moving.
• Notice trigger foods. High-sulfur foods (eggs, red meat, garlic, some cruciferous vegetables) can add to the smell for some people.

2. Over-the-counter options

Commonly suggested OTC remedies include simethicone (Gas-X) for gas, bismuth subsalicylate (Pepto-Bismol) — which can actually bind sulfur gas — and peppermint.^[3] Check with your pharmacist or prescriber before combining anything with your medication.

3. Ginger

Ginger has a long history of use for nausea and settling the stomach, and it's one of the remedies frequently mentioned for GLP-1 digestive discomfort.^[2] A standardized ginger extract delivers a consistent dose of its active compounds (gingerols).

4. Support your gut

Because GLP-1 medications change how food moves through your gut, supporting your digestive system with a probiotic and prebiotic may help overall comfort for some people (here's what to look for in a probiotic for GLP-1). Results vary, and supplements are meant to support digestive comfort — not treat or cure a medical condition. If you already experience significant bloating, introduce any prebiotic fiber gradually, since starting too high can add to gas at first.

The bottom line

Sulfur burps on a GLP-1 come down to slowed digestion and gas — a normal, if unpleasant, side effect for many people. Smaller and lower-fat meals, hydration, targeted OTC options, ginger, and gut support can all help take the edge off while your body adjusts. If it stays severe, loop in your prescriber.